Daratumumab Biosimilar – Anti-CD38 mAb – Research Grade

Reference:
Size

,

Isotype

IgG1, kappa

Brand

Product type

Clonality

Expression system

Applications

,

Product nameDaratumumab Biosimilar - Anti-CD38 mAb - Research Grade
SourceCAS 945721-28-8
SpeciesHomo sapiens
Expression systemMammalian cells
Molecular weight148kDa
Purity>85%
BufferPBS buffer PH7.5
Delivery conditionBlue ice (+4°C)
Delivery lead time in business days3-5 days if in stock; 3-5 weeks if production needed
Delivery Time3-5 days if in stock; 3-5 weeks if production needed
Storage conditionstore at -80°C
BrandProteoGenix
Aliases /SynonymsDaratumumab,HuMax-CD38,CD38,anti-CD38
ReferencePX-TA1213
NoteFor research use only. Not suitable for human use.
IsotypeIgG1-kappa
ClonalityMonoclonal Antibody

Description of Daratumumab Biosimilar - Anti-CD38 mAb - Research Grade

General information on Anti-CD38(Homo sapiens) (Daratumumab) Monoclonal Antibody

Daratumumab is an immunoglobulin G1 kappa monoclonal antibody against CD38+ multiple myeloma cells.

SDS-PAGE for Daratumumab Biosimilar - Anti-CD38 mAb

Daratumumab Biosimilar - Anti-CD38 mAb, on SDS-PAGE under reducing and non-reducing conditions. The gel was stained overnight with Coomassie Blue. The purity of the antibody is greater than 95%.

Daratumumab Biosimilar - Anti-CD38 mAb binds to CD38 Recombinant Protein in indirect ELISA Assay

Immobilized CD38 Recombinant Protein (cat. No.PX-P4081) at 0.5µg/mL (100µL/well) can bind to Daratumumab Biosimilar - Anti-CD38 mAb (cat. No.PX-TA1213) in indirect ELISA with Goat Anti-Human IgG secondary antibody coupled with HRP measured by OD450

Publication

Rebecca J. Brownlie, Ruth Kennedy, Erica B. Wilson, Maja Milanovic, Claire F. Taylor, Dapeng Wang, John R. Davies, Heather Owston, Emma J. Adams, Sophie Stephenson, Rebecca Caeser, Benjamin E. Gewurz, Peter V. Giannoudis, Claudio Scuoppo, Dennis McGonagle, Daniel J. Hodson, Reuben M. Tooze, Gina M. Doody, Gordon Cook, David R. Westhead, Ulf Klein; Cytokine receptor IL27RA is an NF-κB–responsive gene involved in CD38 upregulation in multiple myeloma. Blood Adv 2023; 7 (15): 3874–3890. doi: https://doi.org/10.1182/bloodadvances.2022009044

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