No services found
No Products found
100µg
IgG1
ProteoGenix
COVID-19 products
Monoclonal Antibody
Neutralizing antibodies (NAbs) have been identified as key molecules for the treatment, prevention, and study of the COVID-19 disease. However, NAbs development against pathogenic agents can be a complex process due to the need to assess the neutralizing activity of many candidates in the early stages. Traditional methods of measuring viral neutralization comprise the use time-consuming virus neutralization test (VNT), pseudo-virus neutralization tests (pVNT), or the plaque reduction neutralization test (PRNT) which also require access to facilities with strict pathogen protection levels (biosafety level 3). In the case of SARS-CoV-2, the etiological agent of the COVID-19 disease, NAbs are defined by their ability to block the interaction between the spike protein of the virus, particularly its receptor-binding domain (RBD), and the specific human cell surface receptor (ACE2). The anti-CoV-RBD (G1) antibody belongs to a unique category of antibodies with potential neutralizing activity that have been isolated from a high diversity COVID-19 human antibody library (LiAb-SFCOVID-19™) using the recombinant form of RBD as the target antigen. Moreover, the neutralizing activity of the candidate was screening using our SARS-CoV-2 Surrogate Virus Neutralization Test (sVNT), which detects antibodies able to efficiently compete with ACE2 for the binding pocket of RBD. Additionally, the stability and ease of production of this antibody were validated by producing milligram amounts in the transient mammalian system XtenCHO™. This antibody could serves as an efficient reagent to study COVID-19 disease progression and also as a potential surveillance tool to determine the development of long-term and short-term immunity to SARS-CoV-2 among the world’s population.
Anti-CoV-RBD (G1) antibody, on SDS-PAGE under reducing and non-reducing condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Reviews
There are no reviews yet.
Your email address will not be published. Required fields are marked *
In which application did you use the antibody? * WB ELISA Sandwich ELISA IF IHC IP FC other
Did it work in your application? * Yes No
Your review *
Name *
Email *
Save my name, email, and website in this browser for the next time I comment.
Related products
Got a question or need a quote? Message us and we’ll get back to you 48 hours or less.
First name
Last name
Email address
Lab / Company
Phone number
send
Your cart is currently empty.