size	100ug, 50ug
Brand	ProteoGenix
Product type	Recombinant Proteins
Host Species	Escherichia coli (E. coli)
Applications	Elisa, WB

Signal Transduction Developmental Biology

Product name	Sclerostin (SOST )
Uniprot ID	Q9BQB4
Uniprot link	http://www.uniprot.org/uniprot/Q9BQB4
Expression system	Prokaryotic expression
Sequence	MGHHHHHHMSDSEVNQEAKPEVKPEVKPETHINLKVSDGSSEIFFKIKKTTPLRRLMEAFAKRQGKEMDSLRFLYDGIRIQADQTPEDLDMEDNDIIEAHREQIGGQGSQGWQAFKNDATEIIPELGEYPEPPPELENNKTMNRAENGGRPPHHPFETKDVSEYSCRELHFTRYVTDGPCRSAKPVTELVCSGQCGPARLLPNAIGRGKWWRPSGPDFRCIPDRYRAQRVQLLCPGGEAPRARKVRLVASCKCKRLTRFHNQSELKDFGTEAARPQKGRKPRPRARSAKANQAELENAY
Purity estimated	>40%by SDS-PAGE
Buffer	PBS, pH7.5
Delivery condition	Dry Ice
Delivery lead time in business days	Europe: 5-7 working days USA & Canada: 7-10 working days Rest of the world: 5-12 working days
Storage condition	4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
Brand	ProteoGenix
Host species	Escherichia coli (E.coli)
Applications	ELISA,WB
Fragment Type	Gln24-Tyr213
Aliases /Synonyms	Sclerostin
Reference	PX-P4621
Note	For research use only

Description of Sclerostin (SOST )

General Information about Sclerostin (SOST)

Sclerostin is a protein encoded by the SOST gene in humans. Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain, and its sequence is different from that of the bone morphogenetic protein (BMP) antagonist DAN (differential selection gene in neuroblastoma) . Sclerostin is mainly produced by bone cells, but it can also be expressed in other tissues and has an anti-anabolic effect on bone formation.

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