SIGLEC2 recombinant protein

Reference: PX-P5177-100
Product nameSIGLEC2 recombinant protein
Uniprot linkhttps://www.uniprot.org/uniprot/P20273
Origin speciesHomo sapiens (Human)
Expression systemProkaryotic expression
Molecular weight19.57 kDa
Protein delivered with Tag?N-terminal His Tag
Purity estimated>90% as determined by SDS-PAGE
BufferPBS, pH7.5
Delivery conditionDry Ice
Storage condition4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
BrandProteoGenix
Host speciesEscherichia coli (E.coli)
ApplicationsELISA,WB
Fragment TypeTrp176-Ala330
Protein AccessionP20273
Aliases /SynonymsSialic acid-binding Ig-like lectin 2, Siglec-2, CD22, T-cell surface antigen Leu-14, BL-CAM, B-lymphocyte cell adhesion molecule, B-cell receptor CD22
ReferencePX-P5177
NoteFor research use only

Description of SIGLEC2 recombinant protein

General information on SIGLEC2 recombinant protein

SIGLEC2 Recombinant Protein: Structure and Activity

SIGLEC2 is a member of the CD family of proteins, which are transmembrane receptors that recognize and bind to the sialic acid molecules found on the surface of cells. SIGLEC2 is expressed on the surface of B cells, monocytes, and macrophages, and is involved in immune cell signaling and regulation. The recombinant form of SIGLEC2 is a soluble protein that has been overexpressed in a recombinant expression system. This protein contains a single transmembrane domain and an extracellular domain, which is composed of two immunoglobulin-like domains.

SIGLEC2 Recombinant Protein: Application

The recombinant form of SIGLEC2 can be used in a variety of research applications, including functional assays, immunoassays, and antibody-drug target studies. In functional assays, the recombinant protein can be used to study the interactions between SIGLEC2 and its ligands, such as sialic acid. In immunoassays, the protein can be used to detect and quantify the presence of SIGLEC2 on the surface of cells. Finally, the recombinant protein can be used in antibody-drug target studies to investigate the potential of SIGLEC2 as a therapeutic target.

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