Recombinant Mouse SIGLEC10/SLG2 Protein, N-His

Description of Recombinant Mouse SIGLEC10/SLG2 Protein, N-His

Introduction to Recombinant Mouse SIGLEC10/SLG2 Protein

Recombinant Mouse SIGLEC10/SLG2 Protein is a synthetic protein that is produced through genetic engineering techniques. This protein belongs to the SIGLEC (sialic acid-binding immunoglobulin-like lectin) family and is also known as sialic acid-binding Ig-like lectin 10 (SIGLEC10) or sialic acid-binding Ig-like lectin 2 (SLG2). It is commonly used as an antigen in various research studies and has shown promising results in the field of immunotherapy.

Structure of Recombinant Mouse SIGLEC10/SLG2 Protein

The recombinant mouse SIGLEC10/SLG2 protein is a glycoprotein that consists of 479 amino acids. It has a molecular weight of approximately 57 kDa and is composed of two distinct domains: an extracellular domain and a transmembrane domain. The extracellular domain contains a sialic acid-binding site and an immunoglobulin-like domain, while the transmembrane domain anchors the protein to the cell membrane.

The extracellular domain of SIGLEC10/SLG2 protein is highly glycosylated, with multiple N-linked glycosylation sites. These glycans play a crucial role in the stability and function of the protein. The sialic acid-binding site in the extracellular domain allows the protein to bind to sialic acid-containing molecules on the surface of cells. This binding is important for the recognition and interaction of the protein with other cells.

Activity of Recombinant Mouse SIGLEC10/SLG2 Protein

Recombinant Mouse SIGLEC10/SLG2 Protein has been shown to have a wide range of activities in various biological processes. One of its main functions is its role in immune regulation. The protein is expressed on the surface of immune cells, such as dendritic cells and macrophages, and plays a crucial role in the recognition and regulation of immune responses.

SIGLEC10/SLG2 protein has been found to bind to sialylated glycans on the surface of cancer cells. This binding leads to the activation of signaling pathways that promote the killing of cancer cells by immune cells. This makes the protein a potential target for cancer immunotherapy.

In addition to its role in immune regulation, SIGLEC10/SLG2 protein has also been implicated in other biological processes such as cell adhesion, cell migration, and cell signaling. It has been shown to interact with other proteins and molecules on the cell surface, thereby influencing various cellular functions.

Application of Recombinant Mouse SIGLEC10/SLG2 Protein

Recombinant Mouse SIGLEC10/SLG2 Protein has a wide range of applications in the field of research and medicine. Its ability to bind to sialylated glycans makes it a valuable tool for studying the role of these molecules in various biological processes. The protein is commonly used as an antigen in studies investigating the immune response to cancer and infectious diseases.

Furthermore, SIGLEC10/SLG2 protein has shown promising results in cancer immunotherapy. It has been found to enhance the recognition and killing of cancer cells by immune cells, making it a potential target for the development of new cancer treatments. The protein has also been studied for its potential role in the treatment of autoimmune diseases, as it has been found to regulate the immune response in these conditions.

Conclusion

In conclusion, Recombinant Mouse SIGLEC10/SLG2 Protein is a synthetic protein with a complex structure and diverse activities. Its role in immune regulation and potential applications in cancer immunotherapy make it a valuable tool for research and medicine. Further studies on this protein may lead to the development of new and effective treatments for various diseases.