Recombinant Human PTPRQ Protein, N-His

Description of Recombinant Human PTPRQ Protein, N-His

Introduction

The Recombinant Human PTPRQ Protein is a highly specialized protein that plays a crucial role in various biological processes. This protein is produced through recombinant DNA technology, making it a valuable tool for research and medical applications. In this article, we will discuss the structure, activity, and applications of Recombinant Human PTPRQ Protein.

Structure of Recombinant Human PTPRQ Protein

The Recombinant Human PTPRQ Protein is a transmembrane protein that belongs to the protein tyrosine phosphatase (PTP) family. It is encoded by the PTPRQ gene and is composed of 1,798 amino acids. The protein has a molecular weight of approximately 200 kDa and is found in various tissues, including the brain, kidney, and inner ear.

The structure of Recombinant Human PTPRQ Protein consists of an extracellular domain, a transmembrane domain, and an intracellular domain. The extracellular domain contains three immunoglobulin-like domains, which are responsible for binding to specific ligands. The transmembrane domain anchors the protein to the cell membrane, while the intracellular domain contains the catalytic domain responsible for the protein’s phosphatase activity.

Activity of Recombinant Human PTPRQ Protein

The main activity of Recombinant Human PTPRQ Protein is its phosphatase activity, which involves the removal of phosphate groups from tyrosine residues in target proteins. This activity is crucial for regulating various cellular processes, including cell growth, differentiation, and signaling pathways.

Studies have shown that Recombinant Human PTPRQ Protein is involved in the development and maintenance of the nervous system, particularly in the formation of synapses and myelin. It has also been found to play a role in kidney function and hearing, as mutations in the PTPRQ gene have been linked to kidney and hearing disorders.

Applications of Recombinant Human PTPRQ Protein

Recombinant Human PTPRQ Protein has various applications in both research and medical fields. One of the main uses of this protein is in studying its role in the nervous system. Researchers can use recombinant PTPRQ protein to investigate its function in synapse formation and myelination, which can provide insights into neurological disorders.

In the medical field, Recombinant Human PTPRQ Protein has potential applications in the treatment of kidney and hearing disorders. By understanding the role of this protein in these conditions, targeted therapies can be developed to treat patients with PTPRQ gene mutations.

Additionally, Recombinant Human PTPRQ Protein can also be used as an antigen in diagnostic tests for various diseases. The protein’s specific structure and activity make it a valuable tool for detecting antibodies in patients and studying immune responses to certain diseases.

Conclusion

In summary, Recombinant Human PTPRQ Protein is a crucial protein with a complex structure and diverse activity. Its role in various biological processes makes it a valuable tool for research and medical applications. With further studies and advancements in technology, this protein has the potential to contribute to the understanding and treatment of various diseases.