Recombinant Mouse APCS Protein, N-His

Reference: YMC00101
Product nameRecombinant Mouse APCS Protein, N-His
Origin speciesMouse
Expression systemEukaryotic expression
Molecular weight25.71 kDa
BufferLyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
FormLiquid
Delivery conditionDry Ice
Delivery lead time in business days3-5 days if in stock; 3-5 weeks if production needed
Storage condition4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
BrandAntibodySystem
Host speciesEscherichia coli (E.coli)
Fragment TypeLys25-Asp224
Aliases /SynonymsPtx2, Apcs, Serum amyloid P-component, Sap, SAP
ReferenceYMC00101
NoteFor research use only.

Description of Recombinant Mouse APCS Protein, N-His

Introduction

Recombinant Mouse APCS Protein is a type of protein that is produced using recombinant DNA technology. This technology involves inserting a specific gene into a host organism, such as bacteria, to produce a desired protein. Recombinant Mouse APCS Protein is a highly purified and biologically active protein that has numerous applications in scientific research and medical treatments.

Structure of Recombinant Mouse APCS Protein

Recombinant Mouse APCS Protein is a glycoprotein, meaning it contains carbohydrate molecules attached to it. It has a molecular weight of approximately 25 kDa and is composed of 225 amino acids. The protein has a unique structure, with a single polypeptide chain folded into two domains connected by a disulfide bond. The first domain contains a beta-sheet structure, while the second domain is primarily made up of alpha-helices.

Activity of Recombinant Mouse APCS Protein

Recombinant Mouse APCS Protein is a member of the pentraxin family of proteins and is a key component of the innate immune system. It is primarily produced by the liver in response to inflammation or infection. The main function of Recombinant Mouse APCS Protein is to bind to and remove foreign substances, such as bacteria, viruses, and toxins, from the body. It does this by recognizing and binding to specific molecules on the surface of these foreign substances, also known as antigens.

In addition to its role in the immune system, Recombinant Mouse APCS Protein also has anti-inflammatory properties. It can inhibit the production of inflammatory cytokines, which are proteins that contribute to the inflammatory response. This makes Recombinant Mouse APCS Protein a potential therapeutic target for diseases characterized by excessive inflammation, such as sepsis and rheumatoid arthritis.

Applications of Recombinant Mouse APCS Protein

Recombinant Mouse APCS Protein has a wide range of applications in both scientific research and medical treatments. In research, it is commonly used as a tool to study the immune system and its response to various stimuli. It can also be used to investigate the role of inflammation in different diseases and to develop potential treatments.

One of the main medical applications of Recombinant Mouse APCS Protein is in the treatment of sepsis, a life-threatening condition caused by a severe immune response to an infection. Recombinant Mouse APCS Protein has been shown to improve survival rates in animal models of sepsis by reducing inflammation and improving immune function. Clinical trials are currently underway to evaluate its effectiveness in treating sepsis in humans.

Another potential medical application of Recombinant Mouse APCS Protein is in the treatment of autoimmune diseases, such as rheumatoid arthritis and lupus. These diseases occur when the immune system mistakenly attacks the body’s own tissues. Recombinant Mouse APCS Protein has been shown to have a suppressive effect on the immune system, making it a promising candidate for the treatment of these diseases.

Conclusion

In summary, Recombinant Mouse APCS Protein is a highly purified and biologically active protein with a unique structure and important functions in the immune system. Its ability to bind to and remove foreign substances, as well as its anti-inflammatory properties, make it a valuable tool in scientific research and a potential treatment for various diseases. With ongoing research and clinical trials, the full potential of Recombinant Mouse APCS Protein is yet to be realized.

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