Dalmitamig Biosimilar – Anti-HER1;CD28 mAb – Research Grade

Reference:
Product nameDalmitamig Biosimilar - Anti-HER1;CD28 mAb - Research Grade
SourceBispecific, Bivalent, CAS: 2765077-69-6
Origin speciesHuman
Expression systemXtenCHO
Purity>95% by SDS-PAGE
Buffer0.01M PBS, pH 7.4
Delivery conditionBlue ice (+4°C)
Delivery lead time in business days3-5 days if in stock; 3-5 weeks if production needed
Storage condition4°C for short term; -20°C for long term
BrandProteoGenix
Aliases /Synonymsanti-HER1, Receptor tyrosine-protein kinase erbB-1, Proto-oncogene c-ErbB-1, Epidermal growth factor receptor, EGFR, ERBB1, ERBB, CD28, TP44, T-cell-specific surface glycoprotein CD28
ReferencePX-TA2185-100
NoteFor research use only. Not suitable for human use.
IsotypeIgG4-kappa
ClonalityMonoclonal Antibody

Description of Dalmitamig Biosimilar - Anti-HER1;CD28 mAb - Research Grade

Dalmitamig Biosimilar – Anti-HER1;CD28 mAb – Research Grade: A Revolutionary Therapeutic Antibody

Dalmitamig Biosimilar – Anti-HER1;CD28 mAb – Research Grade is a groundbreaking therapeutic antibody that has shown promising results in the treatment of various diseases. This biosimilar is designed to target the HER1 and CD28 receptors, making it a versatile and effective treatment option for a wide range of conditions.

Structure of Dalmitamig Biosimilar

Dalmitamig Biosimilar is a monoclonal antibody, which means it is made from identical immune cells that are all clones of a unique parent cell. This ensures consistency and specificity in its structure and function. The antibody is composed of two heavy chains and two light chains, each with a unique sequence of amino acids. These chains are held together by disulfide bonds, giving the antibody its characteristic “”Y”” shape.

The variable region of the antibody, also known as the antigen-binding site, is responsible for its specificity. In the case of Dalmitamig Biosimilar, the variable region is designed to bind to both HER1 and CD28 receptors, making it a dual-targeting antibody. This unique feature allows for a more targeted and effective treatment approach.

Mechanism of Action

Dalmitamig Biosimilar works by binding to both the HER1 and CD28 receptors on the surface of cells. The HER1 receptor, also known as epidermal growth factor receptor (EGFR), is a protein that plays a crucial role in cell growth and division. Overexpression of HER1 has been linked to various cancers, making it an important therapeutic target.

The CD28 receptor, on the other hand, is a co-stimulatory molecule that is essential for the activation of T cells, a type of immune cell. By targeting this receptor, Dalmitamig Biosimilar can enhance the immune response and aid in the destruction of cancer cells.

By simultaneously targeting both HER1 and CD28 receptors, Dalmitamig Biosimilar can inhibit the growth and proliferation of cancer cells while also boosting the immune response. This dual mechanism of action makes it a highly effective therapeutic antibody for the treatment of various diseases.

Applications of Dalmitamig Biosimilar

Dalmitamig Biosimilar has shown promising results in the treatment of various conditions, including cancer, autoimmune diseases, and inflammatory disorders. In cancer treatment, it has been particularly effective in targeting HER1-overexpressing tumors, such as non-small cell lung cancer, breast cancer, and head and neck cancer.

In autoimmune diseases, Dalmitamig Biosimilar’s ability to enhance the immune response has shown potential in treating conditions such as rheumatoid arthritis, multiple sclerosis, and psoriasis. It has also been studied for its potential use in the treatment of inflammatory disorders, such as Crohn’s disease and ulcerative colitis.

Research Grade Quality

Dalmitamig Biosimilar is manufactured using the latest biotechnology processes, ensuring high purity and quality. It is also extensively tested to meet the stringent standards of research grade antibodies. This makes it a reliable and consistent tool for scientific research and drug development.

Overall, Dalmitamig Biosimilar – Anti-HER1

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