Lumistobart Biosimilar – Anti-BIT mAb – Research Grade

Reference:
Product nameLumistobart Biosimilar - Anti-BIT mAb - Research Grade
SourceCAS: 2851923-91-4
Origin speciesHuman
Expression systemXtenCHO
Purity>95% by SDS-PAGE
Buffer0.01M PBS, pH 7.4
Delivery conditionBlue ice (+4°C)
Delivery lead time in business days3-5 days if in stock; 3-5 weeks if production needed
Storage condition4°C for short term; -20°C for long term
BrandProteoGenix
Aliases /Synonymsanti-BIT, Signal-regulatory protein alpha-1, Brain Ig-like molecule with tyrosine-based activation motifs, MFR, SIRP, Sirp-alpha-1, Sirp-alpha-2, PTPNS1, SIRPA, SHP substrate 1, CD172 antigen-like family member A, Sirp-alpha-3, Inhibitory receptor SHPS-1, Signal-regulatory protein alpha-3, CD172a, Tyrosine-protein phosphatase non-receptor type substrate 1, MyD-1 antigen, Bit, SHPS-1, Macrophage fusion receptor, Signal-regulatory protein alpha-2, SHPS1, MYD1, p84
ReferencePX-TA2198-100
NoteFor research use only. Not suitable for human use.
IsotypeIgG1-kappa
ClonalityMonoclonal Antibody

Description of Lumistobart Biosimilar - Anti-BIT mAb - Research Grade

Lumistobart Biosimilar – Anti-BIT mAb – Research Grade

Introduction

Lumistobart Biosimilar – Anti-BIT mAb – Research Grade is a therapeutic antibody that has been developed to target the protein BIT, which is involved in various disease processes. This biosimilar has been designed to have similar structure, activity and application as the original anti-BIT monoclonal antibody (mAb), but at a more affordable cost. In this article, we will explore the structure, activity and potential applications of this biosimilar in the field of therapeutics.

Structure of Lumistobart Biosimilar – Anti-BIT mAb

Lumistobart Biosimilar – Anti-BIT mAb is a recombinant humanized monoclonal antibody, which means that it is produced in a laboratory using genetic engineering techniques. It is composed of two identical heavy chains and two identical light chains, each containing a variable region and a constant region. The variable regions are responsible for binding to the target protein, BIT, while the constant regions provide stability and effector functions.

The structure of this biosimilar is very similar to the original anti-BIT mAb, with minor modifications to make it more cost-effective. These modifications do not affect the binding affinity or specificity of the antibody towards BIT, ensuring its therapeutic efficacy.

Activity of Lumistobart Biosimilar – Anti-BIT mAb

The main activity of Lumistobart Biosimilar – Anti-BIT mAb is to bind to the protein BIT and inhibit its function. BIT is a key player in various disease processes, including inflammation, autoimmune disorders, and cancer. By blocking the activity of BIT, this biosimilar can help to alleviate symptoms and slow down disease progression.

Additionally, this biosimilar also has effector functions, such as antibody-dependent cell-mediated cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC). These functions can help to enhance the immune response against BIT-expressing cells, leading to their destruction.

Application of Lumistobart Biosimilar – Anti-BIT mAb

Lumistobart Biosimilar – Anti-BIT mAb has the potential to be used in various therapeutic applications, including the treatment of autoimmune diseases, inflammatory disorders, and cancer. Its ability to specifically target BIT makes it a promising candidate for these conditions, as BIT has been implicated in their pathogenesis.

In autoimmune diseases, BIT is known to play a role in the activation of immune cells and the production of inflammatory cytokines. By blocking BIT, this biosimilar can help to reduce the excessive immune response and alleviate symptoms in conditions such as rheumatoid arthritis and multiple sclerosis.

In inflammatory disorders, BIT is involved in the recruitment and activation of immune cells, leading to tissue damage. By inhibiting BIT, this biosimilar can help to reduce inflammation and prevent tissue damage in conditions such as inflammatory bowel disease and psoriasis.

In cancer, BIT has been found to promote tumor growth and metastasis. By targeting BIT, this biosimilar can potentially inhibit these processes and slow down tumor progression. It can also enhance the immune response against cancer cells, making it a promising addition to cancer treatment regimens.

Conclusion

Lumistobart Biosimilar – Anti-BIT mAb – Research Grade is a promising therapeutic antibody that has been developed to target the protein BIT. It has a similar structure and activity to the original anti-BIT mAb, but at a more affordable cost. This biosimilar has the potential to be used in various therapeutic applications, including autoimmune diseases, inflammatory disorders, and cancer. Its ability to specifically target BIT makes it a valuable addition to the field of therapeutics.

Reviews

There are no reviews yet.

REVIEW YOUR PRODUCT

Be the first to review “Lumistobart Biosimilar – Anti-BIT mAb – Research Grade”

Your email address will not be published. Required fields are marked *

Related products

Alpha-amylase inhibitor 0.19
Antigen

Alpha-amylase inhibitor 0.19

PX-P4285 210€
Cyclin-dependent kinase 4 inhibitor B(CDKN2B)
Antigen

Cyclin-dependent kinase 4 inhibitor B(CDKN2B)

PX-P4865 210€
Human AMH,Muellerian-inhibiting factor recombinant protein
Antigen

Human AMH,Muellerian-inhibiting factor recombinant protein

PX-P4055 210€
Human ANXA5 Recombinant Protein
Antigen

Human ANXA5 Recombinant Protein

PX-P3034 210€
Human BIRC5 Recombinant Protein
Antigen

Human BIRC5 Recombinant Protein

PX-P3036 210€
Human Chuck Recombinant Protein
Antigen

Human Chuck Recombinant Protein

PX-P1080 210€
Human IgG1 LALA Isotype Control antibody (HyHEL-10)
Isotype Control

Human IgG1 LALA Isotype Control antibody (HyHEL-10)

PTX17885 180€

Contact us

Got a question or need a quote?
Message us and we’ll get back to you 48 hours or less.






    Cart (0 Items)

    Your cart is currently empty.

    View Products