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Developing antibodies against cancer targets? Discover the world’s first Human Cancer Phage Display Library
Looking to develop a new therapeutic antibody? Maximize your chances of identifying the best possible candidate to reach clinical phases thanks to ProteoGenix therapeutic antibody discovery services! By partnering with ProteoGenix, you gain access to comprehensive, turnkey solutions—from target production to bioproduction. Whether it’s generating human antibodies against complex targets (including membrane proteins in their native conformation), designing and producing antibody-drug conjugates, or developing stable cell lines capable of yielding titers of several grams per liter, we meet these challenges every day for biotech and biopharma clients of all sizes.
With over 20 years of experience in antibody discovery and development, ProteoGenix has consistently pioneered innovative solutions for the design and production of complex targets, as well as for the discovery of human antibodies against them.
Designing and producing your target are two of the most crucial steps in determining the success of your therapeutic antibody. This process requires antigen design in its native conformation. As experts in gene, peptide, and protein synthesis and expression, we are equipped to produce any type of antigen, including:
The journey to developing a therapeutic antibody begins with generating a high affinity and high specificity fully human antibody. To help you identify your best lead candidates, our scientists have developed three fully human antibody discovery platforms, both in vitro and in vivo (using a humanized mouse platform), that can adapt to any type of antigen —even non-immunogenic and toxic ones.
Phage Display with Human Antibody Libraries:
Single B Cell Screening on Humanized Mice:
Hybridoma Generation on Humanized Mice:
In addition to these three human antibody generation platforms, ProteoGenix also offers advanced nanobody discovery solutions.
ProteoGenix boasts the most comprehensive antibody engineering platform on the market specifically developped for biotech and biopharmaceutical companies. Whether you’re looking to increase antibody affinity, humanize it, or reformat it into CAR-T, bispecific antibodies, or antibody-drug conjugates, we offer a full suite of compehensive antibody engineering services. Furthermore, by combining these services with our AI-powered platforms, we help you accelerate your antibody development.
Bispecific antibody development and production
Antibody-drug conjugate production
Custom CAR-T production
Antibody humanization
Affinity maturation
Developability and manufacturability assessments
The process of developing a therapeutic antibody requires production at various scales—whether for candidate selection, preclinical in vivo and in vitro testing, or clinical lot production. ProteoGenix supports you every step of the way with our three antibody production platforms:
High-throughput antibody production
For dozens or even hundreds of different antibodies in parallel
Recombinant antibody production
Using our proprietary XtenCHOTM platform, ideal for preclinical batches
Stable cell line development
Ready for clinical entry (GMP transition possible with our CDMO partners)
Taking your therapeutic antibody to clinical phases requires critical decision-making at key stages. To ensure you make the right choices, you need a world-class antibody characterization platform and guidance from therapeutic antibody development experts. Our platform provides detailed insights into the structural and functional properties of your biomolecules, including:
Find more detailed information on our antibody characterization platform on our dedicated page.
Expertise in native conformation antigen production
Maximize your chances of ensuring your antibody recognizes its target in vivo.
3 human antibody discovery platforms
Empowering you with the best opportunities to discover antibodies that meet your specific needs.
A unique AI and wet lab combination
This powerful blend allows us to enhance your antibody’s properties and make the right decisions in record time.
Zero risk for you
Our therapeutic antibody discovery process comes with multiple guarantees, allowing you to move forward confidently and risk-free towards bioproduction.
Royalty and IP-free antibodies
At ProteoGenix, we’ve designed a process that’s 100% IP free, so you have full control over your antibody.
A end-to-end solution from antigen design to bioproduction
Trust a single partner to guide you seamlessly from the earliest stages of discovery through to preclinical development.
Our therapeutic antibody discovery service includes a tailored strategy based on your specifications, antigen design and production, and antibody generation, production, and purification, all according to the chosen method.
As experts in therapeutic antibody development, ProteoGenix offers an array of additional services to bring your antibody through to early clinical phases. These can include:
The optimal strategy, with or without these additional services, will be developed in collaboration with one of our therapeutic antibody development experts. Have a project or questions? Feel free to contact us by clicking here.
Partnering with a single provider who has full control of your project is the best way to ensure the right decisions are made at every step. By understanding your goals from the outset, we can integrate specific analyses from the candidate selection stage, particularly around developability and manufacturability, ensuring a smooth and stress-free continuation of your development process.
It’s challenging to give a precise answer since many factors influence the price—such as the complexity of antigen synthesis, immunization technique, selected antibody format, and engineering requirements. Generally, the cost of a full therapeutic antibody development, from antigen synthesis to bioproduction, ranges from tens of thousands to several hundred thousand dollars. For a more accurate estimate specific to your project, it’s best to contact our experts, who will provide a free, personalized quote.
Similar to pricing, the timeline depends on your project’s complexity—such as antigen type, immunization method, antibody format, and required engineering. Typically, a full therapeutic antibody development can take anywhere from a few months to two years.
We offer two main types of guarantees within our therapeutic antibody discovery services. The first relates to antibody generation, where we guarantee to deliver at least three antigen-specific binders. This ensures you will have a minimum of three candidate antibodies at the conclusion of the discovery phase. We also provide yield guarantees during the production phase of your antibody and set various milestones that allow you to halt your project at any point. Our goal is to safeguard your investment and help you confidently progress toward clinical phases!
+ 33 (0)3 90 20 54 70
inquiry-mabs@proteogenix.fr
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