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Brand | |
Product type | |
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Applications |
Product name | Pembrolizumab Biosimilar - Anti-PD1 mAb - Research Grade |
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Source | DrugBank DB09037 |
Species | Human |
Expression system | Mammalian cells |
Molecular weight | 149kDa |
Purity | >85% |
Buffer | PBS pH7.5 |
Delivery condition | Blue ice (+4°C) |
Delivery Time | 3-5 days if in stock; 3-5 weeks if production needed |
Storage condition | 4°C for short term; -20°C for long term |
Brand | ProteoGenix |
Applications | ELISA,WB |
Aliases /Synonyms | Pembrolizumab,Pembrolizumab,PD1,anti-PD1 |
Reference | PX-TA1007 |
Note | For research use only. Not suitable for clinical or therapeutic use. |
Isotype | IgG4 |
Clonality | Monoclonal Antibody |
Pembrolizumab is a humanized antibody used in cancer immunotherapy. This includes to treat melanoma, lung cancer, head and neck cancer, Hodgkin lymphoma, and stomach cancer. It is given by slow injection into a vein. It is an IgG4 isotype antibody that blocks a protective mechanism of cancer cells and thereby, allows the immune system to destroy them. It targets the programmed cell death protein 1 (PD-1) receptor of lymphocytes. It works by targeting the cellular pathway of proteins found on the body’s immune cells and some cancer cells, known as PD-1/PD-L1. This product is for research use only.
Pembrolizumab Biosimilar - Anti-PD1 mAb, on SDS-PAGE under reducing and non-reducing condition. The gel was stained overnight with Coomassie Blue. The purity of the antibody is greater than 95%.
Immobilized CD279 Recombinant Protein (cat. No.PX-P4117) at 0.5µg/mL (100µL/well) can bind to Pembrolizumab Biosimilar - Anti-PD1 mAb (cat. No.PX-TA1007) in indirect ELISA with Goat Anti-Human IgG secondary antibody coupled with HRP measured by OD450
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