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Product name | Pertuzumab Biosimilar - Anti-ERBB2, EGFR2, CD340 mAb - Research Grade |
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Source | CAS 380610-27-5 |
Species | Humanized |
Expression system | Mammalian cells |
Purity | >85% |
Buffer | PBS buffer PH7.5 |
Delivery condition | Blue ice (+4°C) |
Delivery lead time in business days | 3-5 days if in stock; 3-5 weeks if production needed |
Delivery Time | 3-5 days if in stock; 3-5 weeks if production needed |
Storage condition | store at -80°C |
Brand | ProteoGenix |
Applications | ELISA,WB |
Aliases /Synonyms | Pertuzumab,OMNITARG,rhuMAB 2C4,ERBB2, EGFR2, CD340,anti-ERBB2, EGFR2, CD340 |
Reference | PX-TA1058 |
Note | For research use only. Not suitable for human use. |
Isotype | IgG1-kappa |
Clonality | Monoclonal Antibody |
Pertuzumab is a recombinant humanized monoclonal antibody that targets the extracellular dimerization domain (subdomain II) of human epidermal growth factor receptor 2 protein (HER2). It was first used with docetaxel and another HER2-targeting monoclonal antibody trastuzumab to treat metastatic HER2-positive breast cancer. Since then, its indications have been expanded to be used as both neoadjuvant therapy and adjuvant therapy for the treatment of HER2-positive breast cancer with a high risk of recurrence.
Immobilized CD340 Recombinant Protein (cat. No. PX-P4121) at 0.5µg/mL (100µL/well) can bind Pertuzumab Biosimilar - Anti-ERBB2, EGFR2, CD340 mAb (cat. No. PX-TA1058) in indirect ELISA with Goat Anti-Human IgG secondary antibody coupled with HRP measured by OD450 giving an EC50 at 9.566M.
Pertuzumab Biosimilar - Anti-ERBB2, EGFR2, CD340 mAb, on SDS-PAGE under reducing and non-reducing condition. The gel was stained overnight with Coomassie Blue. The purity of the antibody is greater than 95%.
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