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View ProductsCD122 Recombinant Protein
| Size | 100ug |
|---|---|
| Brand | |
| Product type | |
| Host Species | |
| Applications |
| Product name | CD122 Recombinant Protein |
|---|---|
| Uniprot ID | P14784 |
| Uniprot link | http://www.uniprot.org/uniprot/P14784 |
| Origin species | Homo sapiens (Human) |
| Expression system | Eukaryotic expression |
| Sequence | MAAPALSWRLPLLILLLPLATSWASAAVNGTSQFTCFYNSRANISCVWSQDGALQDTSCQVHAWPDRRRWNQTCELLPVSQASWACNLILGAPDSQKLTTVDIVTLRVLCREGVRWRVMAIQDFKPFENLRLMAPISLQVVHVETHRCNISWEISQASHYFERHLEFEARTLSPGHTWEEAPLLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFTTWSPWSQPLAFRTKPAALGKD |
| Molecular weight | 35-45kDa |
| Protein delivered with Tag? | C-terminal His Tag |
| Purity estimated | >90% by SDS-PAGE |
| Buffer | PBS pH7.5 |
| Delivery condition | Dry Ice |
| Storage condition | Store at - 20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. |
| Brand | ProteoGenix |
| Host species | Mammalian cells |
| Applications | ELISA,WB |
| Fragment Type | Met1-Asp239 |
| Aliases /Synonyms | IL2RB |
| Reference | PX-P4103 |
| Note | For research use only |
Description of CD122 Recombinant Protein
General information on CD122 Recombinant Protein:
The interleukin-2 receptor (IL-2R), also known as the β subunit receptor of the β subunit IL-2, subunit of the IL-2 β and IL-2RB receptor, participates in the immune response of T cells. ability to bind interleukin 2, CD122 / IL-2RB exists in three forms. The low affinity form is a monomer of the alpha subunit and does not participate in signal transmission. The intermediate affine form is composed of α / β subunit heterodimers, while the high affinity form is composed of α / β / gamma heterotrimers. Both forms of medium and high affinity for CD122 / IL-2RB are involved in receptor-mediated endocytosis and interleukin-2-mediated mitotic signal transduction. CD122 / IL-2RB expression is limited to older B22 + cells (CD43 + CD24- prepro B cells, fraction A), which can proliferate to IL-2 strongly without any stromal cells, but not to IL-15 A High affinity form of the receptor is expressed in activated T lymphocytes, activated B lymphocytes and activated macrophages. CD122 / IL-2RB plays a role in regulating normal lymphocyte development.
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