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Product name | Stable Isotope Labelled Ipilimumab Biosimilar - Anti-CTLA-4 mAb - Research Grade |
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Source | DrugBank DB06186 |
Species | Human |
Expression system | Mammalian cells |
Molecular weight | 148kDa |
Purity | >95% |
Buffer | PBS pH7.5 |
Delivery condition | Blue ice (+4°C) |
Delivery Time | 3-5 days if in stock; 5-8 weeks if production needed |
Storage condition | 4°C for short term; -20°C for long term |
Brand | ProteoGenix |
Applications | MS |
Aliases /Synonyms | Ipilimumab |
Reference | PX-TA1021-SIL |
Related Products | PX-P4782 |
Note | For research use only. Not suitable for clinical or therapeutic use. |
Isotype | IgG1Kappa |
Clonality | Monoclonal Antibody |
Format | Lyophilized |
Labelling | Arginine: 13C6,15N4 ; Lysine: 13C6,15N2, >99% |
Isotopic Enrichment | 99% |
Stability | 1 year |
Formula | C6572H10126N1734O2080S40 |
Ipilimumab is a monoclonal antibody used in the treatment of melanoma. It is an antibody that inhibits the CTLA-4 checkpoint of T lymphocytes, a checkpoint that certain cancers activate to decrease the efficiency of the lymphocyte. Ipilimumab is a human monoclonal antibody of the IgG1 type directed against the CTLA-4 protein (Cytotoxic T-Lymphocyte Antigen 4). The inhibition of this receptor present on the T lymphocytes results in the activation of the T lymphocyte. This product is for research use only.
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