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Product name | Bamlanivimab Biosimilar - Anti-Covid Spike RBD mAb - Research Grade |
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Species | Humanized |
Expression system | Mammalian |
Molecular weight | 150kDa |
Purity | >85% |
Buffer | PBS pH7.5 |
Delivery condition | Blue ice (+4°C) |
Delivery lead time in business days | 3-5 days if in stock; 3-5 weeks if production needed |
Delivery Time | 3-5 days if in stock; 3-5 weeks if production needed |
Storage condition | 4°C for short term; -20°C for long term |
Brand | ProteoGenix |
Applications | ELISA,WB |
Aliases /Synonyms | Bamlanivimab,Bamlanivimab,Covid Spike RBD,anti-Covid Spike RBD |
Reference | PX-TA1031 |
Note | For research use only. Not suitable for human use. |
Isotype | IgG1 |
Clonality | Monoclonal Antibody |
Bamlanivimab is a synthetic monoclonal antibody (mAb) that was developped from the first blood samples from COVID-19 recovered patients in the United States. Bamlanivimab is a neutralizing IgG1 mAb targetting the SARS-CoV-2 spike, which prevents the virus from entering human cells. It has been found to recognize first type and variants referenced as PX-COV-P046 and PX-COV-P052.
Bamlanivimab Biosimilar - Anti-Covid Spike RBD mAb, on SDS-PAGE under reducing and non-reducing conditions. The gel was stained overnight with Coomassie Blue. The purity of the antibody is greater than 95%.
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This antibody along with other therapeutic antibodies were tested in surrogate virus neutralization test using spike trimers and ACE2 protein. This antibody showed expected neutralization of wild type, Alpha, Gamma, and Delta variants (IC50 135.73 ng/mL for the wild type, 185.54 ng/mL for Alpha, >500 ng/mL for Gamma and Delta).