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View ProductsSize | 100ug |
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Brand | |
Product type | |
Host Species | |
Applications |
Product name | CD19 Recombinant Protein |
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Uniprot ID | P15391 |
Uniprot link | http://www.uniprot.org/uniprot/P15391 |
Origin species | Homo sapiens (Human) |
Expression system | Eukaryotic expression |
Sequence | MPPPRLLFFLLFLTPMEVRPEEPLVVKVEEGDNAVLQCLKGTSDGPTQQLTWSRESPLKPFLKLSLGLPGLGIHMRPLAIWLFIFNVSQQMGGFYLCQPGPPSEKAWQPGWTVNVEGSGELFRWNVSDLGGLGCGLKNRSSEGPSSPSGKLMSPKLYVWAKDRPEIWEGEPPCLPPRDSLNQSLSQDLTMAPGSTLWLSCGVPPDSVSRGPLSWTHVHPKGPKSLLSLELKDDRPARDMWVMETGLLLPRATAQDAGKYYCHRGNLTMSFHLEITARPVLWHWLLRTGGW |
Molecular weight | 45kDa |
Protein delivered with Tag? | C-terminal His Tag |
Purity estimated | >90% by SDS-PAGE |
Buffer | PBS pH7.5 |
Delivery condition | Dry Ice |
Storage condition | Store at - 20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. |
Brand | ProteoGenix |
Host species | Mammalian cells |
Applications | ELISA,WB |
Fragment Type | Met1~Trp290 |
Aliases /Synonyms | / |
Reference | PX-P4077 |
Note | For research use only |
CD19 is a transmembrane glycoprotein expressed on the surface of B cells. It is composed of two extracellular immunoglobulin-like domains and a short cytoplasmic tail.
CD19 plays an important role in the development and function of B cells by mediating signal transduction and cell adhesion. It also interacts with other immune checkpoint proteins to regulate B cell survival, differentiation and activation.
CD19 is an attractive target for antibody-drug conjugates (ADCs) due to its broad expression on B cells. It has been used in clinical trials for the treatment of B cell malignancies such as leukemia and lymphoma.
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