Reslizumab Biosimilar – Anti-IL5 mAb – Research Grade

Reference:
Product nameReslizumab Biosimilar - Anti-IL5 mAb - Research Grade
SourceCAS 241473-69-8
SpeciesHumanized
Expression systemMammalian cells
Purity>85%
BufferPBS buffer PH7.5
Delivery conditionBlue ice (+4°C)
Delivery Time3-5 days if in stock; 3-5 weeks if production needed
Storage conditionstore at -80°C
BrandProteoGenix
ApplicationsELISA,WB
Aliases /SynonymsReslizumab,CDP-835,JES1-39D10,SCH55700,IL5,anti-IL5
ReferencePX-TA1198
NoteFor research use only. Not suitable for clinical or therapeutic use.
IsotypeIgG4-nd
ClonalityMonoclonal Antibody

Description of Reslizumab Biosimilar - Anti-IL5 mAb - Research Grade

General information on Anti-IL5(Homo sapiens) (Reslizumab) Monoclonal Antibody

Reslizumab is a humanized interleukin 5 (IL-5) antagonist monoclonal antibody (IgG4 kappa), produced by recombinant DNA technology in murine non-secretory myeloma 0 (NS0) cells. IL-5 is a pro-inflammatory cytokine responsible for the growth and differentiation, recruitment, activation and survival of eosinophil markers. Elevated levels of eosinophils increase the risk of exacerbation of asthma, including allergic and non-allergic forms of asthma characterized by eosinophilia. By targeting IL-5 and disrupting its signaling pathway, reslizumab aims to inhibit the maturation of eosinophils and promote programmed cell death. Reslizumab is sold as Cinqaero in Europe.

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