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View ProductsDiphtheria toxin
| size | 100ug, 50ug |
|---|---|
| Brand | ProteoGenix |
| Product type | Recombinant Proteins |
| Host Species | Escherichia coli (E. coli) |
| Applications | Elisa, WB |
| Product name | Diphtheria toxin |
|---|---|
| Uniprot ID | P00587 |
| Uniprot link | http://www.uniprot.org/uniprot/P00587 |
| Expression system | Prokaryotic expression |
| Sequence | MKKIWLALAGLVLAFSASAKEASSYDYILGWEFGGGVPEHKKEENMLSHLYVSSKDKENISKENDDVLDEKEEEAEETEE EELEGADDVVDSSKSFVMENFSSYHGTKPGYVDSIQKGIQKPKSGTQGNYDDDWKEFYSTDNKYDAAGYSVDNENPLSGK AGGVVKVTYPGLTKVLALKVDNAETIKKELGLSLTEPLMEQVGTEEFIKRFGDGASRVVLSLPFAEGSSSVEYINNWEQA KALSVELEINFETRGKRGQDAMYEYMAQACAGNRVRRSVGSSLSCINLDWDVIRDKTKTKIESLKEHGPIKNKMSESPNK TVSEEKAKQYLEEFHQTALEHPELSELKTVTGTNPVFAGANYAAWAVNVAQVIDSETADNLEKTTAALSILPGIGSVMGI ADGAVHHNTEEIVAQSIALSSLMVAQAIPLVGELVDIGFAAYNFVESIINLFQVVHNSYNRPAYSPGHKTQPFLHDGYAV SWNTVEDSIIRTGFQGESGHDIKITAENTPLPIAGVLLPTIPGKLDVNKSKTHISVNGRKIRMRCRAIDGDVTFCRPKSP VYVGNGVHANLHVAFHRSSSEKIHSNEISSDSIGVLGYQKTVDHTKVNSKLSLFFEIKSKEASSYDYILGWEFGGGVPEH KKEENMLSHLYVSSKDKENISKENDDVLDEKEEEAEETEEEELEGSHHHHHH |
| Molecular weight | 76.35kDa |
| Purity estimated | >60% by SDS-PAGE |
| Buffer | PBS, pH=7.5 |
| Delivery condition | Dry Ice |
| Delivery lead time in business days | Europe: 5-7 working days USA & Canada: 7-10 working days Rest of the world: 5-12 working days |
| Storage condition | 4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection) |
| Brand | ProteoGenix |
| Host species | Escherichia coli (E.coli) |
| Applications | ELISA,WB |
| Fragment Type | Gly26-Ser560 |
| Aliases /Synonyms | NAD(+)--diphthamide ADP-ribosyltransferase |
| Reference | PX-P4480 |
| Note | For research use only |
Description of Diphtheria toxin
General Information about Diphtheria toxin
Diphtheria toxin is a complete toxin catalyst and protein synthesis inhibitor of ADP-ribosylation of EF-2. Diphtheria toxin from Corynebacterium diphtheriae can inhibit protein synthesis by catalyzing the ADP-ribosylation of eukaryotic aminoacyltransferase II (EF-2). Diphtheria toxin is cell permeable and can be transported across the endosomal membrane in response to low pH3. Diphtheria toxin is synthesized and excreted as an enzyme and must undergo two covalent changes to be activated
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