Gocatamig Biosimilar – Anti-DLL3;CD3e;ALB mAb – Research Grade

Reference:
Product nameGocatamig Biosimilar - Anti-DLL3;CD3e;ALB mAb - Research Grade
SourceTrispecific, CAS: 2851862-91-2
Origin speciesHuman
Expression systemXtenCHO
Purity>95% by SDS-PAGE
Buffer0.01M PBS, pH 7.4
Delivery conditionBlue ice (+4°C)
Delivery lead time in business days3-5 days if in stock; 3-5 weeks if production needed
Storage condition4°C for short term; -20°C for long term
BrandProteoGenix
Aliases /Synonymsanti-Drosophila Delta homolog 3, Delta3, Delta-like protein 3, DLL3, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain, ALB, Albumin
ReferencePX-TA2192-100
NoteFor research use only. Not suitable for human use.
IsotypeIg single chain scFvhl-VH-VH'
ClonalityMonoclonal Antibody

Description of Gocatamig Biosimilar - Anti-DLL3;CD3e;ALB mAb - Research Grade

Introduction

Gocatamig Biosimilar is a therapeutic antibody that targets three key proteins: DLL3, CD3e, and ALB. This biosimilar is a research grade antibody that has been designed to mimic the activity of the original Gocatamig antibody, providing researchers with a more cost-effective option for their studies. In this article, we will discuss the structure, activity, and application of Gocatamig Biosimilar in detail.

Structure of Gocatamig Biosimilar

Gocatamig Biosimilar is a monoclonal antibody, meaning it is produced from a single type of immune cell. It is composed of two heavy chains and two light chains, which are connected by disulfide bonds. The heavy chains are made up of constant and variable regions, while the light chains only have variable regions. The variable regions are responsible for binding to the target proteins, while the constant regions determine the antibody’s effector functions.

Activity of Gocatamig Biosimilar

Gocatamig Biosimilar targets three proteins: DLL3, CD3e, and ALB. DLL3 is a transmembrane protein that is overexpressed in certain types of cancer, including small-cell lung cancer. By targeting DLL3, Gocatamig Biosimilar can potentially inhibit the growth and proliferation of cancer cells. CD3e is a protein found on the surface of T cells, and by binding to it, Gocatamig Biosimilar can activate T cells and enhance their ability to kill cancer cells. ALB is a protein found in the blood that is involved in regulating the immune response. By targeting ALB, Gocatamig Biosimilar can potentially modulate the immune response and enhance the body’s ability to fight cancer.

Application of Gocatamig Biosimilar

Gocatamig Biosimilar is primarily used in research studies to investigate the role of DLL3, CD3e, and ALB in cancer. By targeting these proteins, researchers can gain a better understanding of their function and potential as therapeutic targets. Gocatamig Biosimilar can also be used in preclinical studies to evaluate its efficacy and safety as a potential cancer treatment. Additionally, Gocatamig Biosimilar can be used in diagnostic assays to detect the presence of DLL3, CD3e, and ALB in patient samples, providing valuable information for cancer diagnosis and treatment.

Therapeutic Antibody

Gocatamig Biosimilar is a therapeutic antibody, meaning it is designed to specifically target and treat a disease. Antibodies are a type of protein produced by the immune system to recognize and neutralize foreign substances, such as bacteria and viruses. Therapeutic antibodies, like Gocatamig Biosimilar, are engineered to target specific proteins involved in disease processes, making them a highly targeted and effective treatment option.

Therapeutic Target: DLL3, CD3e, and ALB

The three proteins targeted by Gocatamig Biosimilar – DLL3, CD3e, and ALB – are all involved in cancer. DLL3 is overexpressed in small-cell lung cancer, making it a potential therapeutic target for this type of cancer. CD3e is involved in T cell activation, and enhancing T cell activity can be beneficial in cancer treatment. ALB is involved in regulating the immune response, and targeting it can potentially enhance the body’s ability to fight cancer. By targeting these proteins, Gocatamig Biosimilar has the potential to be an effective therapeutic option for cancer treatment.

Conclusion

Gocatamig Biosimilar is a research grade therapeutic antibody that targets three key proteins involved in cancer: DLL3, CD3e, and ALB. Its structure, activity, and application make it a valuable tool for researchers studying these proteins and their potential as therapeutic targets. With its potential to inhibit

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