Linclatamig Biosimilar – Anti-MEGT1;CD3e mAb – Research Grade

Reference:
Product nameLinclatamig Biosimilar - Anti-MEGT1;CD3e mAb - Research Grade
SourceBispecific, CAS: 2885203-43-8
Origin speciesHuman
Expression systemXtenCHO
Purity>95% by SDS-PAGE
Buffer0.01M PBS, pH 7.4
Delivery conditionBlue ice (+4°C)
Delivery lead time in business days3-5 days if in stock; 3-5 weeks if production needed
Storage condition4°C for short term; -20°C for long term
BrandProteoGenix
Aliases /Synonymsanti-MEGT1, G6D, Megakaryocyte-enhanced gene transcript 1 protein, NG25, LY6G6D, C6orf23, Protein Ly6-D, Lymphocyte antigen 6 complex locus protein G6d, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
ReferencePX-TA2197-100
NoteFor research use only. Not suitable for human use.
IsotypeIgG1-kappa
ClonalityMonoclonal Antibody

Description of Linclatamig Biosimilar - Anti-MEGT1;CD3e mAb - Research Grade

Introduction

Linclatamig Biosimilar – Anti-MEGT1;CD3e mAb – Research Grade is a therapeutic antibody that targets the MEGT1;CD3e protein. This biosimilar is designed to mimic the activity of the original therapeutic antibody, providing a more affordable and accessible treatment option for patients.

Structure of Linclatamig Biosimilar

Linclatamig Biosimilar is a monoclonal antibody, meaning it is derived from a single type of immune cell. It is composed of two identical heavy chains and two identical light chains, which are connected by disulfide bonds. The antibody has a Y-shaped structure, with the two arms of the Y binding to the MEGT1;CD3e protein.

Activity of Linclatamig Biosimilar

The main activity of Linclatamig Biosimilar is to bind to the MEGT1;CD3e protein on the surface of immune cells. This binding triggers a signaling cascade that activates the immune cells, leading to their proliferation and activation. This activation of immune cells is crucial for fighting off infections and diseases.

In addition to its direct activity on immune cells, Linclatamig Biosimilar also has an indirect activity through its ability to bind to the Fc receptors on other cells. This binding can trigger immune responses in these cells, further enhancing the body’s defense mechanisms.

Application of Linclatamig Biosimilar

The main application of Linclatamig Biosimilar is in the treatment of diseases that involve dysregulated immune responses, such as autoimmune diseases and certain types of cancer. By targeting the MEGT1;CD3e protein, this biosimilar can help to regulate and enhance the immune response, leading to improved outcomes for patients.

Some specific diseases that Linclatamig Biosimilar may be used to treat include rheumatoid arthritis, multiple sclerosis, and certain types of leukemia. It may also be used in combination with other therapies to enhance their effectiveness.

Research Grade

Linclatamig Biosimilar is classified as a research grade therapeutic antibody, meaning it is primarily used for research purposes rather than clinical use. This allows scientists and researchers to study its structure, activity, and potential applications in a controlled laboratory setting.

However, as more research and clinical trials are conducted, Linclatamig Biosimilar may eventually be approved for clinical use and become a valuable treatment option for patients.

Conclusion

In summary, Linclatamig Biosimilar – Anti-MEGT1;CD3e mAb – Research Grade is a therapeutic antibody that targets the MEGT1;CD3e protein. Its structure, activity, and application make it a promising candidate for the treatment of various diseases involving dysregulated immune responses. As further research and clinical trials are conducted, this biosimilar may become an important tool in the fight against these diseases.

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