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Plasmodium falciparum PF10Nter Recombinant Protein

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Description
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Product namePlasmodium falciparum PF10Nter Recombinant Protein
Uniprot IDQ8IK14
Uniprot linkhttp://www.uniprot.org/uniprot/Q8IK14
Origin speciesPlasmodium falciparum
Expression systemProkaryotic expression
SequenceMSPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEGDKWRNKKFELGLEFPNLPYYIDGDVKLTQSMAIIRYIADKHN MLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALD VVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGGGDHPPKSDLEVLFQGPLGSMQINPMEKS SFVQTRIFPPKPTIFSLEKNDDFLNTHNEGFLILSYCFAISLFMYIVLKNLYYLYIFKRTRIKIIESLNNDNNVENEIEE MKRVKNLIMEQVIHELMRKSIISKRRTRKDIETDLSQNVRNEDMNLKENEIEMTQVETLKHLIHNNLLTEFHDTKEKNLE SFIKFLQQLMTLEKNEKEFSNNILVKDLMDYIINIGKKEIQKSNTQLSQASSQNYIPSNENDIYIFQIQVIKELLKNNII ITHSNDGKQLDDEIITKILEESLMSQANVVEYFYIEMIKNILGNDYNELNAISYTHDDLYLQKYEKELIKKKLSQYAYKN MNTKQNNKYVQDKTVNKHIHKNQIEQNEATTNLIEKENTFEKTNKFDNNGMIQNNIPIQAETNDESMKNIIQHKELLKNH DKENKNEEIENMNQHKKEECNYNDKKAVTEHSKKSRKNFKRKCMKKRDIRHLYQIDKLQDKILKNLMGQDSIESDSKNND IQQLEEQKSDIQNEKLATSNEQEETRNTNNEHKENEVNMDQNNMKLNIYNLNNQDIQNHYDKNVKEKLEEENILSDNIIK HHHHHH
Molecular weight95,44 kDa
Purity estimated80%
BufferTrisHC 50mMl, 10mM reduced glutathion pH8
Formliquid
Delivery conditionDry Ice
Delivery lead time in business days10-25
Storage condition4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
BrandProteoGenix
Host speciesEscherichia coli (E.coli)
ApplicationsELISA,WB
Fragment TypePartial
Protein AccessionXP_001347311.1*
Spec:Entrez GeneID810184
Spec:SwissProtIDQ8IK14
NCBI ReferenceXP_001347311.1*
Aliases /SynonymsPF10Nter , Tryptophan-rich antigen 3, putative, PF10_0026, PF3D7_1002200
ReferencePX-P1139
NoteFor research use only

Description of Plasmodium falciparum PF10Nter Recombinant Protein

General information on Plasmodium falciparum PF10Nter Recombinant Protein

Tryptophan-rich protein expressed in the late stage schizonts and merozoite stages and because of its association with the surface of merozoites. The protein is localized on the surface of merozoites. The characteristic of the protein is similar to a P. yoelii antigen, pypAg-3, which have been successfully used in vaccination studies in mice. The conservation and uniqueness of the tryptophan-rich domains in plasmodial species, is anindication that it may be an important and essential feature of parasite function.

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Publication

  • 1: Ntumngia FB, Bouyou-Akotet MK, Uhlemann AC, Mordmüller B, Kremsner PG, Kun JF. Characterisation of a tryptophan-rich Plasmodium falciparum antigen associated with merozoites. Mol Biochem Parasitol. 2004 Oct;137(2):349-53. PubMed PMID: 15383306.
  • 2: LaCount DJ, Vignali M, Chettier R, Phansalkar A, Bell R, Hesselberth JR, Schoenfeld LW, Ota I, Sahasrabudhe S, Kurschner C, Fields S, Hughes RE. A protein interaction network of the malaria parasite Plasmodium falciparum. Nature. 2005 Nov 3;438(7064):103-7. PubMed PMID: 16267556.
  • 3: Gardner MJ, Hall N, Fung E, White O, Berriman M, Hyman RW, Carlton JM, Pain A, Nelson KE, Bowman S, Paulsen IT, James K, Eisen JA, Rutherford K, Salzberg SL, Craig A, Kyes S, Chan MS, Nene V, Shallom SJ, Suh B, Peterson J, Angiuoli S, Pertea M, Allen J, Selengut J, Haft D, Mather MW, Vaidya AB, Martin DM, Fairlamb AH, Fraunholz MJ, Roos DS, Ralph SA, McFadden GI, Cummings LM, Subramanian GM, Mungall C, Venter JC, Carucci DJ, Hoffman SL, Newbold C, Davis RW, Fraser CM, Barrell B. Genome sequence of the human malaria parasite Plasmodium falciparum. Nature. 2002 Oct 3;419(6906):498-511. PubMed PMID: 12368864; PubMed Central PMCID: PMC3836256.

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