Recombinant Human EXOC2 Protein, N-GST & C-His

Description of Recombinant Human EXOC2 Protein, N-GST & C-His

Introduction to Recombinant Human EXOC2 Protein

Recombinant proteins are proteins that are produced in a laboratory setting through genetic engineering techniques. These proteins are used in various fields such as medicine, biotechnology, and research. One such recombinant protein is the Recombinant Human EXOC2 Protein, which has gained significant attention due to its unique structure, activity, and potential applications.

Structure of Recombinant Human EXOC2 Protein

The Recombinant Human EXOC2 Protein is a 126-kDa protein that is composed of 1120 amino acids. It is a member of the Exocyst complex, which is a group of proteins that are involved in the transport of vesicles from the Golgi apparatus to the plasma membrane. The protein has a highly conserved N-terminal domain and a C-terminal domain that contains a Sec6/8 binding site. The protein also has a coiled-coil domain that is essential for its interaction with other Exocyst complex proteins.

Activity of Recombinant Human EXOC2 Protein

The main function of Recombinant Human EXOC2 Protein is to facilitate the transport of vesicles containing proteins and lipids from the Golgi apparatus to the plasma membrane. This process is crucial for the maintenance of cell structure and function. The protein achieves this by binding to the Sec6/8 complex and anchoring the vesicles to the plasma membrane. It also plays a role in the formation of cellular protrusions, such as filopodia and lamellipodia, which are essential for cell movement and communication.

Furthermore, studies have shown that Recombinant Human EXOC2 Protein is involved in various cellular processes such as cell division, cell signaling, and cell adhesion. It is also essential for the proper functioning of neurons and has been linked to neurological disorders such as schizophrenia and autism.

Application of Recombinant Human EXOC2 Protein

The unique structure and activity of Recombinant Human EXOC2 Protein make it a valuable tool in various research areas. One of its main applications is in the study of the Exocyst complex and its role in vesicle transport. The protein can be used to investigate the interactions between different Exocyst complex proteins and their functions in cellular processes.

In addition, Recombinant Human EXOC2 Protein has potential therapeutic applications. It has been shown to play a role in cancer cell proliferation and migration, making it a potential target for cancer treatment. Furthermore, the protein has been linked to neurological disorders, and further research may lead to the development of treatments for these conditions.

Recombinant Human EXOC2 Protein is also used in the production of antibodies for diagnostic and research purposes. The protein can be used as an antigen to produce specific antibodies that can be used to detect and study the protein in various tissues and cell types.

Conclusion

In conclusion, Recombinant Human EXOC2 Protein is a unique protein with a crucial role in cellular processes. Its structure and activity make it a valuable tool in research and have potential applications in medicine. Further studies on this protein may lead to a better understanding of its functions and potential therapeutic uses.