Recombinant Human NDUFV2 Protein, N-His

Description of Recombinant Human NDUFV2 Protein, N-His

Structure of Recombinant Human NDUFV2 Protein

The Recombinant Human NDUFV2 Protein is a protein that is produced through the process of recombinant DNA technology. It is a complex protein that is composed of 446 amino acids and has a molecular weight of approximately 50 kDa. The protein is made up of two subunits, alpha and beta, which are encoded by the NDUFV2 gene.

The alpha subunit contains the catalytic domain of the protein, while the beta subunit is responsible for the structural stability of the protein. The two subunits are connected by a linker region and together form the functional enzyme complex.

The crystal structure of the Recombinant Human NDUFV2 Protein has been determined, revealing the three-dimensional arrangement of the amino acids. The protein has a globular shape with several alpha helices and beta sheets, which are important for its enzymatic activity.

Activity of Recombinant Human NDUFV2 Protein

The main function of the Recombinant Human NDUFV2 Protein is to act as a subunit of the NADH dehydrogenase (Complex I) enzyme complex. This enzyme complex is a key component of the electron transport chain, which is responsible for generating ATP, the energy currency of the cell.

The alpha subunit of the Recombinant Human NDUFV2 Protein contains the active site where the oxidation of NADH takes place. This process results in the transfer of electrons to the electron transport chain, leading to the production of ATP.

In addition to its role in energy production, the Recombinant Human NDUFV2 Protein has also been shown to play a role in the regulation of cell death and survival. It has been found to interact with other proteins involved in these processes, indicating its potential role in cellular signaling pathways.

Application of Recombinant Human NDUFV2 Protein

The Recombinant Human NDUFV2 Protein has a wide range of applications in both research and medicine. As a key component of the electron transport chain, it is commonly used in studies related to energy metabolism and mitochondrial function.

In addition, the Recombinant Human NDUFV2 Protein has been used in the development of diagnostic tests for mitochondrial disorders. Mutations in the NDUFV2 gene have been associated with various diseases, making this protein a valuable tool for identifying and studying these conditions.

The protein has also been investigated as a potential therapeutic target for the treatment of diseases such as cancer and neurodegenerative disorders. Its involvement in cellular signaling pathways and regulation of cell death makes it a promising candidate for drug development.

Conclusion

The Recombinant Human NDUFV2 Protein is a complex protein with a crucial role in energy production and cellular signaling. Its structure and function have been extensively studied, and it has a wide range of applications in research and medicine. As our understanding of this protein continues to grow, it may hold even more potential for the development of novel treatments for various diseases.