Recombinant Human WDR46 Protein, N-His

Description of Recombinant Human WDR46 Protein, N-His

Title: Introduction to Recombinant Human WDR46 Protein

Recombinant Human WDR46 Protein is a highly versatile and important protein that plays a crucial role in various biological processes. It is a recombinant form of the WDR46 protein, which is encoded by the WDR46 gene. This protein is widely used in research and biotechnology applications due to its unique structure, activity, and potential therapeutic applications.

Title: Structure of Recombinant Human WDR46 Protein

Recombinant Human WDR46 Protein is a 38 kDa protein that is composed of 337 amino acids. It is a member of the WD repeat protein family, which is characterized by the presence of a conserved WD repeat domain. This domain consists of a series of repeated units of approximately 40 amino acids, each containing a glycine-histidine (GH) dipeptide. The WD repeat domain of WDR46 is responsible for its interaction with other proteins and its role in various cellular processes.

Title: Activity of Recombinant Human WDR46 Protein

Recombinant Human WDR46 Protein has been shown to have multiple activities in different cellular processes. One of its main functions is its role in the assembly and maintenance of the nuclear pore complex (NPC). The NPC is a large protein complex that spans the nuclear envelope and regulates the transport of molecules between the nucleus and the cytoplasm. WDR46 is a key component of the NPC and is essential for its proper functioning.

In addition to its role in the NPC, Recombinant Human WDR46 Protein has also been found to be involved in other cellular processes such as RNA processing and DNA repair. It has been shown to interact with various proteins involved in these processes, suggesting its potential role in regulating their activity.

Title: Applications of Recombinant Human WDR46 Protein

The unique structure and activity of Recombinant Human WDR46 Protein make it a valuable tool for various research and biotechnology applications. One of its main applications is in the study of the NPC and its role in nucleocytoplasmic transport. Recombinant WDR46 protein can be used to study the assembly and disassembly of the NPC and its interaction with other proteins.

Another important application of Recombinant Human WDR46 Protein is in the development of therapeutics. Studies have shown that WDR46 is overexpressed in certain types of cancer, making it a potential target for cancer treatment. Recombinant WDR46 protein can be used to screen for small molecules that can inhibit its activity and potentially be developed into anti-cancer drugs.

Title: Antigenicity of Recombinant Human WDR46 Protein

Recombinant Human WDR46 Protein has also been used as an antigen in immunological studies. Its unique structure and function make it an ideal target for antibody production. Antibodies against WDR46 can be used to study its expression and localization in different tissues and cell types, as well as its potential role in disease.

In conclusion, Recombinant Human WDR46 Protein is a highly versatile and important protein with a unique structure and activity. Its role in various cellular processes and potential therapeutic applications make it a valuable tool for research and biotechnology. With ongoing studies and advancements in protein engineering, the potential of Recombinant Human WDR46 Protein in various fields continues to expand.