XtenCHO ™ Race Cell Bank Pack

Description of XtenCHO ™ Race Cell Bank Pack

The XtenCHO™ Race Cell line has been an internal tool for years at ProteoGenix! These extremely powerful cells are now available for you!
In the last years, biotherapeutics represent more than half of the total approved drugs. Most of them include monoclonal antibodies. Biotherapeutics bear post-translational modifications, are often large and complex. A cell line like XtenCHO™ Race which is able to produce these proteins is a valuable tool for therapeutic development.
ProteoGenix uses this cell line routinely to produce its recombinant protein for its customers. Given the willingness of our customers to use it we now offer it in our catalog.

XtenCHO™ Race Cells characteristics

The XtenCHO™ Race Cells are derived from Chinese Hamster Ovarian CHO-K1 cell line. They have been optimized to sustain extended transient gene expression. The genetic modifications enhance plasmid-driven expression and increase plasmid maintenance. Indeed, the XtenCHO™ Race Cells can maintain the transfected plasmid for 14 days without feeding making them produce on a longer period. The XtenCHO™ Race Cells are well adapted to high-density suspension culture. The XtenCHO™ Expression Medium has been specifically developed to be supplied to these cells for high viability and high growth cultures. The XtenCHO™ Race Cells have a doubling time of approximately 23 hours. These cells are also very robust and easy to cultivate, their recovery time after thawing is about 2 days.
The XtenCHO™ Race Cells provide the highest protein expression level on the market! In combination with the XtenCHO™ Race Transfection Kit, the record yield of 904 mg/mL has been achieved with a recombinant antibody. Moreover, these cells can produce a wide range of proteins and antibodies including pentameric IgMs. Being derived from CHO cells they perform human-like glycosylations and are resistant to viral infections.
The XtenCHO™ Race Cells are key components of the XtenCHO™ Race Starter Kit.

1 box : XtenCHO™ Race Cell Bank Pack : 6 vials

XtenCHO™ Race outperforms up to 6X (Cixutumumab and Peresolimab)

Crude production yields in mg/L obtained in 24-well plates cultures without feeding (Octet Analysis) Yields in flask (better aeration) will be 1.5 to 2.5 Higher for Human/humanized IgG1/IgG4 (depending on the antibody considered)