Antibody production
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Antibody productionAre murine monoclonal antibodies still relevant for modern medicine?
Philippe Funfrock
Murine monoclonal antibodies were the first antibodies ever to be produced at lab-scale thanks to the discovery of the hybridoma technology in 1975. To date, very few of these antibodies…
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Essential steps for the successful manufacturing of therapeutic antibodies
In a specific sense, antibody production steps include the synthesis and purification of the antigen (peptide, protein, or DNA), the… Read More
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How antibody development can enhance the functionality of monoclonal antibodies for therapeutic applications
Antibody development consists in the modification and engineering of monoclonal antibodies. These techniques can be used to increase or decrease… Read More
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The benefits of pairing monoclonal and polyclonal antibodies for custom immunoassay development
In a previous article, we highlighted the benefits and drawbacks of using monoclonal and polyclonal antibodies. In this article,… Read More
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Interview of Pr. Bérangère BIHAN-AVALLE, expert in Phage Display Technology
Bérangère BIHAN-AVALLE, researcher at the Enzyme and Cell Engineering Unit UMR 7025 CNRS (GEC) and expert in Phage Display Technology,… Read More
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Primary antibodies and ELISA – all you need to know to design your immunoassay
Immunoassays use primary antibodies for the detection and quantification of specific antigens in different types of samples. To date, ELISA… Read More
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The benefits and limitations of using hybridoma technology to discover new antibodies
The hybridoma technology, first developed in 1975 by Köhler and Milstein is considered one of the greatest breakthroughs in the… Read More
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In vivo vs. in vitro techniques for custom antibody generation
The first stage of custom antibody generation consists of the creation and maturation of these molecules in vivo (immunization) or… Read More
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Tips to choose the best monoclonal antibody production process for your project
Early monoclonal antibody production processes relied on the use of immortalized hybridoma cell lines. However, these early production methods faced… Read More
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Antibody synthesis: How it works and how to leverage it to develop new drugs
The development of any successful antibody therapy starts by first understanding the process of antibody synthesis and its role in… Read More
